Central Activator Keeps the Circadian Clock Ticking

Most living organisms have adapted their physiology and behavior to match the daily cycle of light and dark generated by the rotation of the earth, operating with a period of approximately 24 hours. Control of this rhythmic behavior—the “circadian clock”—is largely conserved. To understand the inner workings of the circadian clock, researchers determined the 3D structure of the transcriptional activator complex that is its central positive component.

Summary Slide Handout